UJI AKTIVITAS ANTIBAKTERI EKSTRAK ETANOL DAUN LEGUNDI (Vitextrifolia L.) TERHADAP PERTUMBUHAN Staphylococcus epidermidis

Authors

  • Jon Kenedy Marpaung Program Studi D3 ANAFARMA, Universitas Sari Mutiara Indonesia
  • Panal Sitorus Program Studi S1 Farmasi, Universitas Sari Mutiara Indonesia
  • Pandapotan Nasution Program Studi S1 Farmasi, Universitas Sari Mutiara Indonesia
  • Roma Devina Yanti Program Studi S1 Farmasi, Universitas Sari Mutiara Indonesia

DOI:

https://doi.org/10.51544/jf.v7i2.2770

Abstract

Legundi leaves (Vitextrifolia L.) contain flavonoid compounds, alkaloids and saponins, tannins, steroids/triterpenoidsthatact as antiseptic substancesandaid in the wound healing process. Staphylococcusepidermidis (Gram positive) is a mild skin infection-causing bacteria that accompanies the formation of abscesses. As for the purpose of this study To know the absence of antibacterial activity from concentrations of 10%, 15%, 20%, 25% legundileaf extractagainst Staphylococcus epidermid is bacteria and know the effective concentration of legunleaf extract in in hibiting the growth of Staphylococcus epidermidis bacteria. This research methoduses experimental methods and legundileaf extract with concentrations of 10%, 15%, 20%, 25%. The resultsshowedthatconcentrationsof 10%, 15%, 20%, 25% of legundileaf ethanol extract had antibacterial activity against the growth of Staphylococcus epidermidisindicated with a blockable zone diameter of 8 mm, 8.84 mm, 9.84 mm, 10.54 mm, respectively. Base dont here search that has beendone can be concluded that legundileaf extractcan inhibit the growth of bacteria Staphylococcus epidermidis, because around the discpaperthere is a clear zone that indicates the absence of bacterial growth.

Downloads

Download data is not yet available.

References

Hariana, A. (2013). Tumbuhan Obat dan Khasiatnya. Jakarta: Penebar Swadaya. Halaman 138-139.

Lubis, H. M. L., & Hariaji, I. (2017).Ekstrak buah legundi (Vitextrifolia L.) mampu menghambat pembelahan dan pertumbuhan sel tumor kulit tikus, 17(1), 1-6.

Herbie, T. 2015. Kitab Tanaman Berkhasiat Obat 226. Cetakan Pe. Editedby Adhe. Depok Sleman Yogyakarta: OCTOPUS Publishing House.

Radji, Maksum (2010). Buku Ajar Mikrobiologi. Jakarta: Buku Kedokteran EGC. Halaman: 125, 127, 130, 132, 137.

Depkes RI , 2010. Pedoman Pemberantas Penyakit Diare. Jakarta:dan PL Diakses pada tanggal 30 mei 2006

Iqlima, 2016.Uji Aktivitas Ekstrak Daun Legundi terhadap Penurunan Kadar Glukosa Darah Pada Mencit.Jurnal Ilmiah Mahasiswa Pendidikan Kimia (JIMPK).Vol 2. No 2 (99-106).

Depkes RI. (1995). Materia Medika Indonesia.JilidVI.Jakarta: Departemen Kesehatan RI. Halaman 1-6, 323-325.

Dwidjoseputro, 2010.Dasar-Dasar Mikrobiologi.Penerbit Jembatan: Jakarta.

Depkes RI. (2000). Parameter Standar Umum Ekstrak Tumbuhan Obat. Cetakan Pertama. Jakarta. Departemen Kesehatan RI. Halaman 1,9-10.

Jawetz, E., dkk. (2010). Mikrobiologi Kedokteran.Edisi Kedua puluh. Jakarta: Penerbit EGC. Halaman 239-240, 259.

Pelczar, M. (2012) Dasar-Dasar Mikrobiologi Jilid 2. Jakarta: UI.

Marjoni, Riza. (2016). Dasar-Dasar Fitokimia. Jakarta: Trans Info Media. Halaman: 8-13,15-16, 23.

Nurrahmania, dkk (2014).Identifikasi dan Uji Bioaktivitas Senyawa Metabolit Sekunder Ekstrak Klorofom Daun Tembelekan. Halaman 41-52.

Radji, Maksum (2014). Mekanisme Aksi Molekuler Antibiotik dan Komoterapi.Jakarta: Buku Kedokteran EGC. Halaman: 75-76.

Downloads

Published

2020-12-26