Formulasi Sediaan Masker Gel Pell- Off Ekstrak Etanol Daun Kopi Arabika (Coffea Arabica) Sebagai Anti- Aging

Authors

  • Christica Ilsanna Surbakti Fakultas Farmasi dan Ilmu Kesehatan Universitas Sari Mutiara Indonesia
  • Artha Yuliana Sianipar Fakultas Farmasi dan Ilmu Kesehatan Universitas Sari Mutiara Indonesia
  • Syukur Berkat Waruwu Fakultas Farmasi dan Ilmu Kesehatan Universitas Sari Mutiara Indonesia

Keywords:

formulation, pell-off gel mask, ethanol extract of Arabica coffee leaves, anti-aging

Abstract

Background: Arabica coffee leaves contain phenolic compounds and flavonoid compounds which act as antioxidants. Purpose: To find out whether arabica coffee leaf extract can be formulated in the form of an anti-aging pell-off gel mask. To find out at what concentration the arabica coffee leaf extract pell-off gel mask provides the best activity. Method: Arabica coffee leaf extract is made by maceration. Extract tested screening. Preparation of pell-off gel masks with concentrations of F0 (blanko), F1 (1%), F2 (3%), F3 (5%). Evaluation of the pell-off mask preparation included preparation stability, homogeneity, PH, irritation to volunteer skin, drying time, viscosity, spreadability, and anti-aging effectiveness using a skin analyzer. Results: Simplicia contains alkaloids, flavonoids, tannins, saponins, phenols, steroids. The resulting pell-off mask preparation of ethanol extract of Arabica coffee leaves is homogeneous, PH 5.1-6.1 stable in 4 weeks storage, does not irritate the skin and takes 22- 30 minutes to dry, spreadability is 5-7.5 cm and viscosity 7500- 27050cp. Conclusion: Arabica coffee leaf ethanol extract pell-off gel mask provides better anti- aging effectiveness for 4 weeks. F3(5%) pell-off gelmask provides better anti-aging effects than other formulas.

Downloads

Download data is not yet available.

References

Ansel HC, (1989). Pengantar bentuk sediaan farmasi,Ed 4.Penerjemah Farida Ibrahim. Jakarta: Universitas Indonesia Press.

Durai, P., Thapa, D., Kumari, R., & Malathi, M. (2020). Aging in Elderly :Chorological Versus Photoaging. Indian J. Dermatol, 57(5), 343-352.

Hekimi S, lapointe J,Wen Y. (2011). Taking a ʻʻgoodʼʼ look at free radicals in the aging process. Cell Press : Vol .21 hal.10

Lucida, H., Fitri, E., Pitricia, D., & Hosiana, V.(2017).Formulasi masker pell-off dari ekstrak etanol kulit buah asam kendis (Garcinia cowa, Roxb) Dan Uji aktivitas antioksidannya. Jurnal sains dan teknologi farmasi, 19(1).31-36.

Musfira, (2020).Estimasi Penawaran Komoditas Kopi Di Kabupaten Bulukumba. Skripsi. Makassar: Universitas Muhamadiyah Makassar.

Nasution, H. M. (2020). Skrining Fitokimia dan Isolasi Senyawa Steroid/

Triterpenoid dari Ekstrak N-Heksana Rumput Laut. Jurnal Dunia Farmasi.

Nirmala, F.M., Saputri, G. A. R., & Marcellia, S. (2021). Formulasi sediaan Facial Wash Kombinasi Perasan Jeruk Lemon (Citrus Limon L). Dan Ekstrak Buah Tomat (Solanum Lycopercium L). Sebagai Anti Bakteri Propionibacterium Acnes. Jurnal Mandala Pharmacon Indonesia, 7(2), 188-206.

Noviyanty, Yuska, Asri Mei Linda, et al. (2020). Profil fitokimia senyawa metabolit sekunder ekstrak etanol bunga senduduk (melastoma malabathricum l). Journal of Pharmaceutical and Sciences 3 (1): 1–6.

Oktaviani,L.R, Tamara, G.E, dan Oktavia, E.(2021). Efektivitas ektrak kopi sebagai antioksidan dalam mengatasi photoaging. Pharmaceutical Journal Of Indonesia.

Pandel, R., Poljsak, B., Godic, A., & Dahmane, R. (2020). Skin Photoaging

and The Role of Antioxidants in Its Prevention. ISRN Dermatology, 1-11.

Putriana, Norisca, Aliza, & Sausan, Rihhadatulaisy, (2019) Farmaka vol:18 No.1 Fakultas Farmasi Universitas Padjadjaran.

Rifqa choirunnisa, (2017) formulasi dan uji mutu fisik sediaan mask gel dari jagung(Zea Mays Sacharatta. L) dengan menggunakan variasi basis gel. Universitas Islam Negeri Alaudin, Makassar (Diakses 16 April 2021).

Solin, H. (2019). Formulas Sediaan Masker Gel Pell-Off Dari Ekstrak Daun Bidara (Ziziphus spinachristi L.). Karya Tulis Ilmiah, 79.

Utama. R. F., 2017. Formulasi dan Uji Efek Anti-Aging Dari Krim Mengandung Ekstrak Kulit Buah Jeruk Nipis (Uji aurantifolia (Christin. & Panzer) Swingle). Fakultas Farmasi, Universitas Sumatera Utara.

Wenas, D. M., Aliya, L. S. dan Janah, N. U. 2020. Aktivitas Antiinflamasi Ekstrak Etanol Daun Kopi Arabika (Coffea Arabica L.) Pada Edema Tikus. Buletin Penelitian Tanaman Rempah dan Obat, 31(2), hal. 75.

Zubaydah, W. Fandinata, S. (2020). Formulasi Sediaan Masker Gel Peel off Dari Ekstrak Buah Tomat (Solanum Lycopersicum L.) Beserta Uji Aktivitas Antioksidan.Universitas Halu Oleo.

Downloads

Published

2023-11-30